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Welcome to elastix: a toolbox for rigid and nonrigid registration of images.

elastix is open source software, based on the well-known Insight Segmentation and Registration Toolkit (ITK). The software consists of a collection of algorithms that are commonly used to solve (medical) image registration problems. The modular design of elastix allows the user to quickly configure, test, and compare different registration methods for a specific application. A command-line interface enables automated processing of large numbers of data sets, by means of scripting. Nowadays elastix is accompanied by SimpleElastix, making it available in languages like C++, Python, Java, R, Ruby, Octave, C#, and Lua.


The authors of elastix are Stefan Klein and Marius Staring. Their contact information:

Stefan KleinMarius Staring
http://www.bigr.nl/people/StefanKlein http://elastix.isi.uu.nl/marius

This software was initially developed at the Image Sciences Institute (ISI), under supervision of:

Josien P.W. Pluim

on funding granted by the Netherlands Organization for Scientific Research (NWO). Since May 2008, Marius Staring is employed with the Leiden University Medical Center, Division of Image Processing and Stefan Klein with the Erasmus Medical Center, Biomedical Imaging Group Rotterdam. See the wiki for acknowledgments to other contributors.

If you use this software anywhere we would appreciate if you cite the following articles:

S. Klein, M. Staring, K. Murphy, M.A. Viergever, J.P.W. Pluim, "elastix: a toolbox for intensity based medical image registration," IEEE Transactions on Medical Imaging, vol. 29, no. 1, pp. 196 - 205, January 2010. download doi
D.P. Shamonin, E.E. Bron, B.P.F. Lelieveldt, M. Smits, S. Klein and M. Staring, "Fast Parallel Image Registration on CPU and GPU for Diagnostic Classification of Alzheimer’s Disease", Frontiers in Neuroinformatics, vol. 7, no. 50, pp. 1-15, January 2014. download doi

How to use this documentation

  • For a short introduction to elastix, what it can do and how it is used, see the About page.
  • The binaries and sources can be downloaded from the Download page. You can download the elastix manual for a lot of information regarding the use of elastix.
  • For an extensive documentation of the source code see the doxygen generated Documentation pages.

Mailing list

You can subscribe to the mailing list to stay informed about new developments of elastix, and to communicate with other users and the developers. The following link will take you to the subscription page:

Subscribe to the elastix mailing list.

Once you have subscribed, you can send emails to .

last modified: 24-05-2016 | Copyright 2004 - 2016 © by Stefan Klein & Marius Staring | elastix logo