"Semi-automatic Reference Standard Construction for Quantitative Evaluation of Lung CT Registration"

Keelin Murphy, Bram van Ginneken, Josien P.W. Pluim, Stefan Klein and Marius Staring


An algorithm is presented for the efficient semi-automatic construction of a detailed reference standard for registration in thoracic CT. A well-distributed set of 100 landmarks is detected fully automatically in one scan of a pair to be registered. Using a custom-designed interface, observers locate corresponding anatomic locations in the second scan. The manual annotations are used to learn the relationship between the scans and after approximately twenty manual marks the remaining points are matched automatically. Inter-observer differences demonstrate the accuracy of the matching and the applicability of the reference standard is demonstrated on two different sets of registration results over 19 CT scan pairs.



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Copyright © 2008 by the authors. Published version © 2008 by Springer Lecture Notes in Computer Science. Personal use of this material is permitted. However, permission to reprint or republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution to servers or lists, or to reuse any copyrighted component of this work in other works, must be obtained from the copyright holder.


BibTeX entry

author = "{Keelin Murphy and Bram van Ginneken and Josien P.W. Pluim and Stefan Klein and Marius Staring}",
title = "{Semi-automatic Reference Standard Construction for Quantitative Evaluation of Lung CT Registration}",
booktitle = "{Medical Image Computing and Computer-Assisted Intervention}",
editor = "{G. Fichtinger and A. Martel and T. Peters}",
series = "{Lecture Notes in Computer Science}",
volume = "{5242}",
pages = "{1006 - 1013}",
month = "{September}",
year = "{2008}",

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