"Towards Local Estimation of Emphysema Progression Using Image Registration"
Marius Staring, M. Els Bakker, Denis P. Shamonin, Jan Stolk, Johan H.C. Reiber and Berend C. Stoel
Progression measurement of emphysema is required to evaluate the health condition of a patient and the effect of drugs. To locally estimate progression we use image registration, which allows for volume correction using the determinant of the Jacobian of the transformation. We introduce an adaptation of the so-called sponge model that circumvents its constant-mass assumption. Preliminary results from CT scans of a lung phantom and from CT data sets of two patients suggest that image registration may be a suitable method to locally estimate emphysema progression.