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"MR-based contour propagation for rectal cancer patients"

Sander Uilkema, Uulke A. van der Heide, Jan-Jakob Sonke, Marius Staring and Jasper Nijkamp

Abstract

In rectal cancer patients large day-to-day target volume deformations occur, leading to large PTV margins. The introduction of MR-guided RT with excellent soft-tissue contrast, facilitates adaptive procedures, like online re-planning with smaller margins. Time constraints demand for automatic contouring of the daily-MR. A possible fast solution is contour propagation with deformable image-registration (DIR). In rectal cancer patients DIR is challenging because of large local deformations of the CTV (meso-rectum) caused by (dis)appearing rectal and bladder content. To deal with this challenge, pre-treatment delineations can be used to define a region-of-interest (ROI) to limit DIR to the part of the anatomy, and also allows excluding regions with (dis-)appearing content. In this study, we investigate optimal parameter settings of MR-to-MR DIR, in the context of contour-propagation of the meso-rectum.

 

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Copyright © 2016 by the authors. Published version © 2016 by . Personal use of this material is permitted. However, permission to reprint or republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution to servers or lists, or to reuse any copyrighted component of this work in other works, must be obtained from the copyright holder.

 

BibTeX entry

@inproceedings{Uilkema:2016,
author = "{Sander Uilkema and Uulke A. van der Heide and Jan-Jakob Sonke and Marius Staring and Jasper Nijkamp}",
title = "{MR-based contour propagation for rectal cancer patients}",
booktitle = "{18th International Conference on the use of Computers in Radiation Therapy}",
editor = "{Uwe Oelfke and Mike Partridge}",
address = "{London, UK}",
month = "{June}",
year = "{2016}",
}

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